A trio of experts speak out during the big rounds of the WCM-Q

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An expert on low-carb ketogenic diets and two authorities on Brugada syndrome, a heart disorder, spoke during the final episodes of the Weill Cornell Medicine-Qatar (WMC-Q) Grand Rounds.

Dr William Yancy, associate professor of medicine at Duke University and director of the Duke Lifestyle and Weight Management Center in Durham, NC, discussed the benefits of low-carb diets and some of their downsides in terms of weight loss and diabetes management. , with reference to his own research and other studies in the literature.

Highlighting a systematic review that analyzed perceptions of hunger while following a variety of diets, Dr Yancy explained that people on a low-carbohydrate diet (defined as less than 20g of carbohydrate per day) reported greater fullness. , less hunger and less desire to eat. compared to other regimes. Research also shows that low-carb diets were also found to be more effective for long-term weight loss than low-fat diets and resulted in an increase in HDL (good cholesterol) while also lowering. slightly or not affecting LDL (bad cholesterol). Low-carbohydrate diets also resulted in a reduction in harmful triglyceride levels, allowed people with diabetes to reduce their medication, reduced the incidence of hypoglycemic events, lower blood pressure, and resulted in a reduction levels of hemoglobin A1C (which is associated with diabetes). People on low-carbohydrate diets also had higher levels of daily energy expenditure than people on low-fat or other diets.

However, Dr Yancy pointed out a number of unwanted side effects of low-carb diets, including water loss, sodium deficiency, fatigue, dizziness, constipation, headache, weakness, bad breath, diarrhea and muscle cramps. He said these symptoms were more common in the first two weeks of a low-carb diet and could be alleviated with increased fluid and sodium intake, the use of constipation remedies, and adequate consumption of vegetables.

Dr Yancy said: “Low-carb diets have unique benefits including decreased hunger, increased daily energy expenditure, reduced hemoglobin A1C, reduced hypoglycemic events, greater weight loss and allow diabetic patients to reduce and in some cases stop taking their diabetes medication entirely. But it can also cause side effects, especially when people are just starting a low-carb diet, and so it’s important to focus on fluid intake, especially in the first couple of weeks, and even Advise a sodium supplement to help people maintain hydration and avoid symptoms such as dizziness, headaches, fatigue, and constipation that can occur with dehydration.

Dr Amar Salam, Senior Consultant Cardiologist and Head of Cardiology at Al-Khor Hospital, Hamad Medical Corporation (HMC), and Dr Rasha Kaddoura, Chief Pharmacy Specialist at HMC Heart Hospital, gave a presentation titled ” Brugada Syndrome, The New Silence Killer: What Every Doctor Should Know About It. ”Brugada is a genetic disorder characterized by abnormal electrical activity in the heart that causes abnormal heart rhythms and increases the risk of sudden death in the heart. cardiac origin It is more common in men and in people of Asian descent, and symptoms often appear alongside febrile episodes.

Dr Salam explained the diagnostic criteria for Brugada syndrome, which are based on patient presentation, use of ECG tests, review of family history and genetic testing. Dr Kaddoura and Dr Salam then discussed which drugs to use to manage the disease, including drugs to counter ion current imbalances and antiarrhythmics such as quinidine and bepridil. They also explained which drugs should be avoided as they could be harmful to people with Brugada syndrome and discussed two illustrative case studies.

Dr Salam said: “There is a great deal of interest in Brugada syndrome because it is a relatively new disease for all of us and can kill people. So it is good that so many healthcare professionals are interested in learning how to recognize this syndrome. What I hope people will find most useful and memorable about is how to recognize Brugada syndrome from an ECG test.

Both conferences have been accredited locally by the Department of Health Professions of the Ministry of Public Health – Accreditation Section and internationally by the Accreditation Council for Continuing Medical Education (ACCME).

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